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Drug ReportsTechnetium (99mtc) sestamibi
Technetium tc 99m sestamibi
Technetium Tc-99m Sestamibi (technetium tc 99m sestamibi) is a small molecule pharmaceutical. Technetium tc 99m sestamibi was first approved as Technetium tc 99m sestamibi on 2008-09-22.
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name
Status
Last Update
cardioite2006-02-22
cardioliteNew Drug Application2022-12-06
kit for the preparation of technetium tc 99m sestamibiANDA2013-09-13
kit for the preparation of technetium tc 99m sestamibi injectionANDA2012-01-26
kit for the preparation of technetium tc99m sestamibiANDA2024-09-10
kit for the preparation of technetium tc99m sestamibi injectionANDA2010-04-23
sestamibiunapproved drug other2012-05-23
technetium tc 99m sestamibiANDA2022-05-19
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
V: Various drug classes in atc
— V09: Diagnostic radiopharmaceuticals
— V09G: Cardiovascular system diagnostic radiopharmaceuticals
— V09GA: Technetium (99mtc) compounds
— V09GA01: Technetium (99mtc) sestamibi
HCPCS
No data
Clinical
Clinical Trials
63 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Coronary artery diseaseD003324—I25.1—3311017
HyperparathyroidismD006961EFO_0008506E21.3——1146
Primary hyperparathyroidismD049950EFO_0008519E21.0——1124
Myocardial infarctionD009203EFO_0000612I21———123
InfarctionD007238EFO_0009463————123
Diabetes mellitusD003920HP_0000819E08-E13———213
Type 2 diabetes mellitusD003924EFO_0001360E11———112
HypercalcemiaD006934HP_0003072E83.52———1—1
Type 1 diabetes mellitusD003922EFO_0001359E10———1—1
Thyroid neoplasmsD013964EFO_0003841————1—1
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Myocardial ischemiaD017202EFO_1001375I20-I25—33—713
Coronary diseaseD003327———23—49
Parathyroid neoplasmsD010282———12—13
AdenomaD000236———12—13
Parathyroid diseasesD010279—E21.5——1—12
Mucocutaneous lymph node syndromeD009080EFO_0004246M30.3111——2
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369—C80—2——24
Heart diseasesD006331EFO_0003777I51.9—1——34
Kidney neoplasmsD007680EFO_0003865C64—1——23
Ovarian neoplasmsD010051EFO_0003893C56—1——12
Lung neoplasmsD008175HP_0100526C34.9011———2
Uterine cervical neoplasmsD002583HP_0030159——1———1
Cardiovascular diseasesD002318HP_0001626——1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Breast neoplasmsD001943EFO_0003869C502———1416
Molecular imagingD057054——1————1
Triple negative breast neoplasmsD064726——1————1
GliomaD005910EFO_0000520—1————1
Diffuse intrinsic pontine gliomaD000080443——1————1
Non-small-cell lung carcinomaD002289——1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Renal cell carcinomaD002292EFO_0000376—————22
Chest painD002637HP_0100749R07.9————22
FatigueD005221HP_0012378R53.83————11
Myocardial reperfusionD015425——————11
Acute coronary syndromeD054058EFO_0005672—————11
Angina pectorisD000787EFO_0003913I20————11
Unstable anginaD000789EFO_1000985I20.0————11
Ventricular remodelingD020257——————11
IschemiaD007511EFO_0000556—————11
GalactorrheaD005687——————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTechnetium tc 99m sestamibi
INN—
Description
Technetium (99mTc) sestamibi (INN) (commonly sestamibi; USP: technetium Tc 99m sestamibi; trade name Cardiolite) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six (sesta=6) methoxyisobutylisonitrile (MIBI) ligands. The anion is not defined. The generic drug became available late September 2008. A scan of a patient using MIBI is commonly known as a "MIBI scan".
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID109581-73-9
RxCUI—
ChEMBL IDCHEMBL4594241
ChEBI ID—
PubChem CID25199598
DrugBank—
UNII ID—
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
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Additional graphs summarizing 152 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
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812 adverse events reported
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